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Alemtuzumab vs. Interferon Beta-1a in Early Multiple Sclerosis
NEJM 359:1786-1801,1838, The CAMMS223 Trial Investigators, 2008
See this aricle in Pubmed

Article Abstract
In patients with early, relapsing-remitting multiple sclerosis, alemtuzumab was more effective than interferon beta-1a but was associated with autoimmunity, most seriously manifesting as immune thrombocytopenic purpura. The study was not powered to identify uncommon adverse events.
 
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advances in neurology
adverse drug reaction
alemtuzumab
complications
idiopathic thrombocytopenic purpura
immunomodulation
interferon
interferon beta 1-a
monoclonal antibodies
multiple sclerosis
multiple sclerosis,relapsing
multiple sclerosis,treatment of
T cell lymphocytes
treatment of neurologic disorder

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